A few years ago I heard about a drug that the military was testing on soldiers. This drug was used to treat narcolepsy (people who fall asleep instantly at random times).
The side effect of the drug was that a soldier could stay TOTALLY ALERT and awake for up to 5 days without any serious side effects. This was not a stimulant... it actually some how removed the need for sleep. They didn't feel sleep deprived or "drugged". At the end of 5 days, they sleep off the effects for about 10 hours, so there is no crash.
When I heard this report on the radio, the person being interviewed suggested that if this drug became available to the public as "recreational" it would change the world. A person could have "2 lives" literally. They could work during the day and... play all night or even work all night.
Ever since I heard about this that one time on the radio... I never heard anything about it again... I sooooo want that drug baby!
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The key to those long work sessions is to take small naps. A short nap can do wonders. If you have to work around the clock even an hour here or there can help you get through.
Don't drink a lot of caffeine. If your body has too much caffeine it has the opposite effect and makes you sleepy.
-vern